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Advances in the care of the child with cancer the importance of histologic subclassification of tumors
Author(s) -
Favara Blaise E.,
Galliani Carlos A.,
Wakely Paul E.
Publication year - 1986
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19860715)58:2+<426::aid-cncr2820581305>3.0.co;2-m
Subject(s) - medicine , context (archaeology) , nosology , clinical significance , pathology , cancer , radiology , paleontology , biology
Abstract The importance of histologic Subclassification of tumors lies principally in the correlation between nosology and tumor biology, including response to therapy. Subclassifications that are practically achieved, reproducible and uniquely predictive are of great value. As new methods are engaged and new clinical data are reported, classifications may be changed. Subclassifications of solid tumors with proven therapeutic application are exemplified by renal tumors and lymphomas that are commonly referred to as “favorable” or “unfavorable histology.” Subclassification of soft tissue sarcomas, neuroblastoma and tumors of the central nervous system are being investigated, but are presently of undetermined relevance. Classifications and Subclassifications of solid tumors of children are presented in the context of prognostic relevance. Cancer 58:426‐441, 1986.