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Beta‐chain human chorionic gonadotropin‐producing leiomyosarcoma of the small intestine
Author(s) -
Meredith Ruby F.,
Wagman Lawrence D.,
Piper James A.,
Mills A. Scott,
Neifeld James P.
Publication year - 1986
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19860701)58:1<131::aid-cncr2820580123>3.0.co;2-9
Subject(s) - leiomyosarcoma , medicine , nausea , immunoperoxidase , human chorionic gonadotropin , vomiting , sarcoma , gonadotropin , pathology , gynecology , gastroenterology , hormone , immunology , antibody , monoclonal antibody
A 22‐year‐old patient with primary leiomyosarcoma of the small bowel presented with symptoms including nausea and vomiting, a symptom complex similar to hyperemesis gravidarum in the pregnant female. She was found to have elevated levels of serum beta‐HCG which were localized to the leiomyosarcoma cells utilizing an immunoperoxidase staining technique. Thus, this patient presents evidence that beta‐HCG may be produced by sarcoma cells and, therefore, that beta‐HCG may be used as a tumor marker in some sarcoma patients. Cancer 58:131–135, 1986.