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Adult neuroblastoma report of three cases and review of the literature
Author(s) -
Allan Simon G.,
Cornbleet Michael A.,
Carmichael James,
Arnott Sidney J.,
Smyth John F.
Publication year - 1986
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19860615)57:12<2419::aid-cncr2820571228>3.0.co;2-v
Subject(s) - medicine , neuroblastoma , presentation (obstetrics) , radiation therapy , abdomen , surgery , malignancy , incidence (geometry) , stage (stratigraphy) , chemotherapy , survival rate , el niño , pediatrics , paleontology , genetics , physics , optics , biology , cell culture
Adult neuroblastoma is an uncommon malignancy. The authors report three additional cases and review the 39 reported cases in the world literature. Presentation in the abdomen is the most common; a high rate of lower limb presentation is also observed. Incidence is equal between sexes with a median age of presentation of 34 years. Survival is greatest after surgical intervention (median, 20.5 months) compared with no surgery (median, 12.5 months). Chemotherapy may benefit individual patients but does not have a major impact on survival. Radiotherapy is indicated for localized, inoperable primaries or painful metastases. The survival rates of this group of patients parallels that of childhood neuroblastoma, Stage III‐IV. Cancer 57:2419–2421, 1986.