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Thermoradiotherapy for persistent cancer in previously irradiated fields
Author(s) -
Irish C. Edwin,
Brown Jay,
Galen William P.,
Gallucci John J.,
Hyman Milton D.,
Horowitz Irving J.,
Snedecor Philip A.,
Baker Harvey W.
Publication year - 1986
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19860615)57:12<2275::aid-cncr2820571207>3.0.co;2-b
Subject(s) - medicine , hyperthermia , radiation therapy , cancer , radiology , surgery , nuclear medicine
Among some 300 patients undergoing clinical trails with localized radiofrequency hyperthermia, 42 whose cancers had persisted or recurred after conventional radiotherapy were selected for additional limited radiation plus hyperthermia. There were 10 complete responses to therapy, 13 partial responses and one patient was considered nonevaluable. In the remaining 18 patients there was minor regression, stabilization or progression of the tumor. After completion of treatment, five of the tumors appeared operable and surgical resection was accomplished in four. The results of this study support the concept that hyperthermia has a potentiating effect when used in conjunction with radiation therapy. Cancer 57:2275–2279, 1986.