Premium
Alpha‐fetoprotein‐producing pancreatoblastoma. A case report
Author(s) -
Iseki Mikiro,
Suzuki Toshio,
Koizumi Yukihiko,
Hirose Makoto,
Laskin William B.,
Nakazawa Shimpei,
Ohaki Yoshiharu
Publication year - 1986
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19860501)57:9<1833::aid-cncr2820570921>3.0.co;2-p
Subject(s) - medicine , pancreas , neoplasm , pathology , lesion , immunohistochemistry , alpha fetoprotein , germ cell tumors , hepatocellular carcinoma , chemotherapy
A case of pancreatoblastoma, arising in the tail of the pancreas with metastases to the right radius, in an 8‐year‐old boy is reported. The serum alpha‐fetoprotein (AFP) level was over 13 times the normal value before surgery, but returned to normal after removal of the primary tumor. Furthermore, AFP was detected in tumor tissue by immunohistochemistry. This case, representing the second reported primary non‐germ cell pancreatic neoplasm in a child producing elevated serum AFP, supports the use of serum AFP in diagnosing this lesion.