Premium
Sulphomucin colonic type intestinal metaplasia and carcinoma in the stomach. A histochemical study of 115 cases obtained by biopsy
Author(s) -
Huang CunBing,
Xu Jian,
Huang JieFei,
Meng XianYong
Publication year - 1986
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19860401)57:7<1370::aid-cncr2820570721>3.0.co;2-j
Subject(s) - intestinal metaplasia , medicine , biopsy , gastroenterology , metaplasia , pathology , stomach , carcinoma , cancer , incidence (geometry) , colonic carcinoma , physics , optics
One hundred fifteen gastroscopic biopsy specimens (54 cases of carcinoma and 61 of gastritis) were used in this histochemical study. Intestinal metaplasia (IM) was classified into small intestinal type (ST) and colonic type (CT). The former may be a reactive change only. The incidence of sulphomucin colonic type (SCT) metaplasia was higher in gastric carcinomas than in benign lesions ( P < 0.01)and a relation between SCT metaplasia and cancer was demonstrated by both histologic and histochemical procedures. This suggests that SCT IM is correlated with certain precancerous lesions. There was no significant difference in the incidence of O‐acetyl sialomucin colonic type (OCT) metaplasia between benign and malignant diseases. Further study is needed to determine why slightly more than half of the SCT IM was accompanied by OCT IM.