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Staging and therapy of orbital lymphomas
Author(s) -
Bennett Charles L.,
Putterman Allan,
Bitran Jacob D.,
Recant Wendy,
Shapiro Charles M.,
Karesh James,
Kalokhe Urmi
Publication year - 1986
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19860315)57:6<1204::aid-cncr2820570624>3.0.co;2-2
Subject(s) - medicine , lymphoma , radiology , medical diagnosis , abdomen , stage (stratigraphy) , chemotherapy , bone marrow , orbit (dynamics) , pathology , surgery , paleontology , engineering , biology , aerospace engineering
Ten patients with non‐Hodgkin's lymphoma primarily affecting the orbital region were evaluated at Michael Reese Hospital and Medical Center, Chicago, between 1976 and 1983. Diagnoses were based on the histopathologic classification systems of the Working Formulation of the Non‐Hodgkin's Lymphomas and Rappoport. Sequential staging procedures performed at the time of diagnosis included liver‐spleen scans, Technecium‐99 bone scans, gallium 67 scans, computerized axial tomograms of the orbit and abdomen, bone marrow examination and cerebral spinal fluid analyses. Adverse prognostic factors included the following: orbital bone erosions, Stage IV disease, and large cell or mixed cell, diffuse histologic features. The type of histopathologic findings combined with the results of sequential staging procedures is useful in identifying those patients who would benefit most from systemic chemotherapy.