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Lobular carcinoma of the breast in a patient with klinefelter's syndrome. A case with bilateral, synchronous, histologically different breast tumors
Author(s) -
Sanchez Asunción García,
Villanueva Augusto García,
Redondo Clara
Publication year - 1986
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19860315)57:6<1181::aid-cncr2820570619>3.0.co;2-t
Subject(s) - medicine , lobular carcinoma , pathology , klinefelter syndrome , breast cancer , chromosomal abnormality , abnormality , carcinoma , breast carcinoma , cancer , ductal carcinoma , karyotype , biochemistry , chemistry , psychiatry , chromosome , gene
A case of bilateral breast cancer in a patient with a Klinefelter mosaic syndrome is presented. The tumor in the left breast was an infiltrating lobular carcinoma with characteristic in situ component. To the knowledge of the authors, this is the first case in the English literature of lobular carcinoma of the breast in a phenotypic man. In fact, it was the pathologic diagnosis which led to the study of the chromosomal abnormality.