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Transformation of hodgkin's disease into malignant fibrous histiocytoma
Author(s) -
Suster Saul
Publication year - 1986
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19860115)57:2<264::aid-cncr2820570213>3.0.co;2-v
Subject(s) - medicine , lesion , disease , transformation (genetics) , component (thermodynamics) , pathology , malignant transformation , biology , biochemistry , physics , gene , thermodynamics
The continuity that exists between Hodgkin's disease and the fibrohistiocytoses has only recently been recognized. Four cases are presented that illustrate this phenomenon. The fibrohistiocytic component of the Hodgkin's lesion may lag behind the lymphoreticular component, may be present in equal proportion, or may assume a dominant role, with the emergence of a frank fibrohistiocytosis or fibrous histiocytoma being evidenced as the lymphoreticular component recedes.