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Mucin in carcinomas of the thyroid
Author(s) -
Mlynek MariaLieselotte,
Richter Hans Joachim,
Leder LutzDietrich
Publication year - 1985
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19851201)56:11<2647::aid-cncr2820561119>3.0.co;2-8
Subject(s) - mucin , medicine , thyroid , pathology , medullary carcinoma , medullary cavity , differential diagnosis , mucinous carcinoma , anaplastic carcinoma , carcinoma , thyroid carcinoma , adenocarcinoma , cancer
One hundred forty‐two cases of thyroid carcinomas were studied to assess the frequency with which mucinous deposits occur within the neoplastic cells. In contrast to the literature, which contains only a few scattered reports on this topic, the production of mucin by carcinomas of the thyroid was relatively frequently observed in our material. Almost one half of the cases displayed mucinous substances, which occurred in about 50% of the papillary and the medullary carcinomas, 35% of the follicular types, and about 21% of the anaplastic varieties. The amount of mucinous substances varied considerably: 28 cases were weakly positive, 30 cases were moderately positive, and 6 cases were strongly positive. These findings are discussed with respect to diagnostic and differential diagnostic problems, especially with respect to the interpretation of mucinous deposits that occur in metastatic carcinomata.