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Small cell carcinoma of the urinary bladder with hypercalcemia
Author(s) -
Reyes Cesar V.,
Soneru Ileana
Publication year - 1985
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19851115)56:10<2530::aid-cncr2820561035>3.0.co;2-4
Subject(s) - small cell carcinoma , medicine , urinary bladder , pathology , carcinoma , cytoplasm , lung , enolase , cell , small cell lung carcinoma , immunohistochemistry , biology , microbiology and biotechnology , genetics
This report describes three cases of undifferentiated small cell carcinoma of the urinary bladder. Their light microscopic appearance is closely akin to the small cell carcinoma of lung. The neoplastic cells exhibit few cytoplasmic dense core neurosecretory granules ultrastructurally and immunoreactivity to enolase. Two patients manifested clinically hypercalcemia which is rare in small cell carcinoma in general and, to the best of our knowledge, has not been described in association with bladder small cell carcinoma.