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Stage III endometrial carcinoma. A review of 90 cases
Author(s) -
Mackillop William J.,
Pringle John F.
Publication year - 1985
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19851115)56:10<2519::aid-cncr2820561033>3.0.co;2-m
Subject(s) - medicine , stage (stratigraphy) , radiation therapy , carcinoma , surgery , retrospective cohort study , disease , gynecology , paleontology , biology
The authors present a retrospective review of 90 cases of Stage III endometrial carcinoma seen over a 10‐year period at the Princess Margaret Hospital, Toronto. Overall 5‐year survival was 45.5% and disease‐free survival was 36.0%. Prognostic factors identified within Stage III were tumor grade, geographic distribution of disease, the presence of symptoms other than vaginal bleeding or discharge, and completeness of surgery. Isolated involvement of the ovary or fallopian tube emerges as a distinct syndrome with a good prognosis (5‐year survival of 82.3%). Surgery is the treatment of choice for operable cases, but 13 of 36 patients with inoperable disease who completed radical radiotherapy were alive and free of disease at 5 years.