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Osteogenic and sarcomatoid differentiation of a renal cell carcinoma
Author(s) -
Macke Ruth A.,
Hussain Mohammad B.,
Imray Thomas J.,
Wilson Richard B.,
Cohen Samuel M.
Publication year - 1985
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19851115)56:10<2452::aid-cncr2820561021>3.0.co;2-c
Subject(s) - medicine , carcinoma , pathology , renal cell carcinoma , sarcomatoid carcinoma , cancer research
Sarcomatoid renal cell carcinoma is an uncommon renal tumor, and osteogenic differentiation has been reported in only a few of these tumors. The authors report such a case with radiographic, light microscopic, and electron microscopic findings, which demonstrate that the sarcomatiod areas of the tumor are derived from the malignant epithelial cells, retaining epithelial features such as desmosomes and lumina with microvilli. The use of electron microscopy is important in the establishment of this diagnosis.