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Thymic hyperplasia following successful chemotherapy. A report of two cases and review of the literature
Author(s) -
Carmosino Linda,
Dibenedetto Anthony,
Feffer Stephen
Publication year - 1985
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19851001)56:7<1526::aid-cncr2820560709>3.0.co;2-x
Subject(s) - medicine , chemotherapy , hyperplasia , disease , cancer , oncology , pathology
True thymic hyperplasia is rare in adults. The authors have encountered this entity in two patients who were deemed disease‐free following combination chemotherapy for malignant disease. It cannot be assumed that the development of a mediastinal mass or its persistence following chemotherapy is due to recurrent or residual disease. The interrelationship between the immunosuppressive effects of neoplasia and chemotherapy with the resultant thymic overgrowth remains to be clarified. Cancer 56: 1526‐1528, 1985.