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Revision of the world health organization classification of brain tumors for childhood brain tumors
Author(s) -
Rorke Lucy Balian,
Gilles Floyd H.,
Davis Richard L.,
Becker Laurence E.
Publication year - 1985
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19851001)56:7+<1869::aid-cncr2820561330>3.0.co;2-0
Subject(s) - medicine , classification scheme , nomenclature , brain tumor , medulloblastoma , pathology , biology , taxonomy (biology) , botany , information retrieval , computer science
A classification for childhood brain tumors based upon revision of nomenclature of all brain tumors published by the World health Organization (WHO) in 1979 is proposed. Applicability of the WHO classification scheme was tested in a combined study of the clinical and pathologic features of approximately 3300 brain tumors in children. It was found to be adequate for many of the neoplasms but unsuitable for a significant proportion, including a number of complex cerebral tumors for which there was no appropriate name. Nomenclature of poorly differentiated or densely cellular neuroepithelial tumors was simplified to reflect the current state of knowledge of neuroembryology and neuro‐oncology, although the Committee members recognized that such a proposal would likely perpetuate the longstanding and continuing controversy relative to the nature and origin of these neoplasms. Cancer 56: 1869‐1886, 1985.