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Testicular germ cell tumors. A review of 10 years' experience
Author(s) -
Grover Rajesh K.,
Kaushal Vivek,
Gupta Brahm D.
Publication year - 1985
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19850915)56:6<1251::aid-cncr2820560605>3.0.co;2-v
Subject(s) - medicine , seminoma , radiation therapy , mediastinum , germ cell tumors , stage (stratigraphy) , chemotherapy , presentation (obstetrics) , surgery , paleontology , biology
Experience with 200 cases of testicular tumors seen over a period of 10 years has been presented. Modes of presentation, response to treatment, and patterns of failure have been analyzed in 186 cases of germ cell tumors. The role of radiation in the overall management of seminomas is reaffirmed, and the need for adjuvant radiation to the supraclavicular region and mediastinum is demonstrated in Stage II cases of seminoma. Results of treatment with radiation alone or combined with chemotherapy were not encouraging in nonseminomas in the current series. The advantages of an aggressive multimodal approach with judicious combination of surgery, radiation treatment, and combination chemotherapy have been discussed, with review of relevant literature.