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The sézary syndrome with rapid pulmonary dissemination
Author(s) -
Foster Gregory H.,
Eichenhorn Michael S.,
van Slyck Ellis J.
Publication year - 1985
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19850901)56:5<1197::aid-cncr2820560538>3.0.co;2-h
Subject(s) - medicine , cyclophosphamide , hypoxemia , biopsy , lung , vincristine , mycosis fungoides , catheter , lung biopsy , surgery , lymphoma , chemotherapy , pathology
The authors report the case of a patient with long‐standing Sézary syndrome who developed the acute onset of bilateral pulmonary infiltration, severe hypoxemia, and hypotension. Initial diagnostic considerations centered around infection, but an open‐lung biopsy revealed “mycosis fungoides” without evidence of an infectious process. The patient showed striking improvement when given vincristine and cyclophosphamide, but ultimately died 3 months later of a nonpulmonary catheter‐related infection. This rare clinical association stresses the value of open lung biopsy as a diagnostic measure even in desperately ill individuals.