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Chemotherapy for metastatic merkel cell carcinoma
Author(s) -
George Timothy K.,
Anthony Sant'Agnese P. Di,
Bennett John M.
Publication year - 1985
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19850901)56:5<1034::aid-cncr2820560511>3.0.co;2-l
Subject(s) - merkel cell carcinoma , merkel cell , medicine , chemotherapy , pathology , carcinoma , neuroendocrine tumors , neuroendocrine differentiation , oncology , small cell carcinoma , cancer , prostate cancer
Merkel cell carcinomas (also known as trabecular carcinomas) are primary cutaneous small cell neuroendocrine neoplasms with the potential to metastasize. Control of disseminated disease is therefore important. A case of metastatic Merkel cell carcinoma with an excellent response to chemotherapy is presented. The regimen chosen for this case is similar to that used for bronchogenic small cell anaplastic carcinoma. The reason for selecting this regimen was the common neuroendocrine differentiation and the similar histopathologic features of these two tumors. Only a few reports have described chemotherapy for Merkel cell carcinoma and similar agents were used. These cases are reviewed and critically analyzed.