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Carcinoma of the paranasal sinuses results of a prospective pilot study
Author(s) -
Knegt Paul P.,
De Jong Pieter C.,
Van Andel Jacob G.,
De Boer Maarten F.,
Eykenboom Wilhelmina,
Van Der Schans Enno
Publication year - 1985
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19850701)56:1<57::aid-cncr2820560110>3.0.co;2-#
Subject(s) - paranasal sinuses , medicine , prospective cohort study , general surgery , surgery
Sixty patients with paranasal sinus cancer were treated from January 1976 until July 1981 according to a standard protocol in which surgery is combined with a low dose of irradiation and a topically applied cytostatic drug. The local control rate was 65%. Mutilation was clearly reduced. The actuarial 2‐year and 5‐year survival rate was 76% and 65%, respectively. The actuarial 5‐year survival rate for squamous cell carcinoma and undifferentiated carcinoma of the maxillary sinus was 52%. For adenocarcinoma of the ethmoid sinus the actuarial 5‐year survival rate was 100%. The results of this prospective pilot study suggest that it may be possible to achieve better results with less aggressive treatment.