Premium
Ultrastructural investigation of anaplastic salivary gland carcinomas in Eskimos
Author(s) -
Sehested Maxwell,
Hainau Bo,
Albeck Henrik,
Nielsen Niels Højgaard,
Hansen Jens Peder Hart
Publication year - 1985
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19850601)55:11<2732::aid-cncr2820551135>3.0.co;2-#
Subject(s) - pathology , lymphoepithelioma , salivary gland , ultrastructure , anaplastic carcinoma , medicine , carcinoma , basal cell , nasopharyngeal carcinoma , radiation therapy
Ultrastructural investigation of 19 malignant lymphoepithelial salivary gland tumors in Greenland Eskimos disclosed evidence of epithelial origin of the tumor cells in 18 cases. Furthermore, tumor cells exhibited markers of squamous cell differentiation in 16 cases. Signs of adenomatous differentiation were never encountered. Thus, the malignant lymphoepithelial tumor of salivary glands is the ultrastructural counterpart to the nasopharyngeal anaplastic carcinoma (malignant lymphoepithelioma), both being high‐grade squamous cell carcinomas.