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Bone metastasis in hepatocellular carcinoma
Author(s) -
Okazaki Nobuo,
Yoshino Masahiro,
Yoshida Takanobu,
Hirohashi Setsuo,
Kishi Kiyozo,
Shimosato Yukio
Publication year - 1985
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19850501)55:9<1991::aid-cncr2820550927>3.0.co;2-f
Subject(s) - medicine , hepatocellular carcinoma , bone metastasis , metastasis , autopsy , carcinoma , lung , pathology , cancer
Bone metastasis was observed in 16.1% or in 14 of 87 male autopsy cases of hepatocellular carcinoma. The primary tumor within the liver was located in the right lobe in all but one case. There were six patients who first presented with signs attributable to bone metastasis, and lung metastasis subsequently became evident in five of them. These 6 patients lived significantly longer as compared with 8 other patients with bone metastases and 73 patients without. The possible route by which hepatocellular carcinoma cells were carried to the bone is discussed.