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Prognostic value of the topographic grid method in women with T2 N— breast cancer. Statistical results from a series of 203 patients
Author(s) -
Noel Patrick,
Chauvin Franck,
Bailly Christiane,
Clavel Michel,
Mayer Marcel,
Bobin Jean Yves,
Blondet Remi,
Crozet Bruno,
Zlatoff Patrick,
Tcheou Mien,
Pommatau Emile
Publication year - 1985
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19850501)55:9<1987::aid-cncr2820550926>3.0.co;2-1
Subject(s) - medicine , breast cancer , lymph node , adjuvant therapy , oncology , mastectomy , cancer , dissection (medical) , estrogen receptor , series (stratigraphy) , gynecology , surgery , paleontology , biology
In 1977, the authors described the grid method, a topographic technique for mapping the microscopic spread of breast cancer. The current report describes the relapse‐free survival of a series of 203 patients with T2 N— mammary cancer (T2 N0 N1 ab N—) who were treated by mastectomy and regional lymph node dissection and have been followed since 1974. A good prognosis did not prevent relapse in 15% to 20% of patients within the first 5 years. To determine whether the grid method can identify patients at high risk within this group, disease‐free survival and survival were compared in two subsets, a “limited” group (L) and a “diffuse” group (D). The difference between the two groups was statistically significant for both parameters (88%) versus 77% and 93% versus 85% after 5 years ( P < 0.01 and P < 0.02). Other prognostic measures were uniformative. Thus, the grid method has a good prognostic score when compared with the factors usually measured—menopausal status, estrogen receptors, histologic type—and could be used to select appropriate adjuvant therapy in breast cancer.