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Variation in the clinical courses of adult T‐cell leukemia
Author(s) -
Kawano Fumio,
Yamaguchi Kazunari,
Nishimura Hiromichi,
Tsuda Hiroyuki,
Takatsuki Kiyoshi
Publication year - 1985
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19850215)55:4<851::aid-cncr2820550424>3.0.co;2-j
Subject(s) - medicine , chemotherapy , acute leukemia , leukemia , chronic leukemia , oncology , intensive care medicine
Twenty‐nine cases of adult T‐cell leukemia were classified into four types according to the clinical features and course: smoldering, chronic, crisis, and acute. Only 2 of 14 patients with the acute type responded to therapy. The four types showed apparent differences in clinical features, complications, and prognosis, suggesting the need for different therapeutic regimens. For smoldering and chronic cases, no chemotherapy is recommended. However, in crisis and acute cases, aggressive chemotherapy is necessary, although the acute type cases showed extremely poor prognosis despite the most aggressive chemotherapy.