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Small bowel cancers, B‐cell lymphatic leukemia, and six primary cancers with metastases and prolonged survival in the cancer family syndrome of lynch
Author(s) -
Love Richard R.
Publication year - 1985
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19850201)55:3<499::aid-cncr2820550304>3.0.co;2-i
Subject(s) - medicine , cancer , colorectal cancer , oncology , lynch syndrome , leukemia , pathology , dna mismatch repair
The Cancer Family Syndrome of Lynch (CFS) is characterized by the frequent occurrence of multiple types of cancers, often adenocarcinomas of the colon, endometrium, and breast, at early ages in a pedigree pattern suggesting an autosomal dominant mechanism of inheritance. An unusual CFS pedigree is presented in which members exhibited rare cancers, six primary cancers, and prolonged survival.