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Immunoperoxidase study on adenomatoid tumor of the epididymis using anti‐mesothelial cell serum
Author(s) -
Mucientes Francisco,
Govindarajan Sugantha,
Burotto Susanella
Publication year - 1985
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19850115)55:2<363::aid-cncr2820550211>3.0.co;2-d
Subject(s) - mesothelial cell , adenomatoid tumor , immunoperoxidase , carcinoembryonic antigen , mesothelium , antigen , pathology , keratin , medicine , cytoplasm , staining , immunohistochemistry , biology , antibody , immunology , cancer , microbiology and biotechnology , monoclonal antibody
The mesothelial origin of epididymal adenomatoid tumor is supported by the current study for the presence of mesothelial antigen in the tumor cells. By an indirect immunoperoxidase technique, anti‐mesothelial cell serum showed positive cytoplasmic staining in five of the six adenomatoid tumors studied. Previous findings of the presence of strong cytoplasmic keratin and the absence of carcinoembryonic antigen and Factor VIII‐related antigen in these tumor cells are also confirmed by this study.