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Familial adult T‐cell leukemia
Author(s) -
Miyamoto Yuichi,
Yamaguchi Kazunari,
Nishimura Hiromichi,
Takatsuki Kiyoshi,
Motoori Tadashi,
Morimatsu Minoru,
Yasaka Tatsuomi,
Ohya Ippei,
Koga Teruto
Publication year - 1985
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19850101)55:1<181::aid-cncr2820550128>3.0.co;2-e
Subject(s) - leukemia , medicine , t cell leukemia , transmission (telecommunications) , antibody , antigen , virus , virology , immunology , electrical engineering , engineering
Two siblings who developed adult T‐cell leukemia (ATL) are presented. The patient and 7 of 26 healthy family members examined had the serum antibodies against ATL‐associated antigens (ATLA). This family study shows that two main routes of transmission of human T‐cell leukemia virus (HTLV) may be involved: one is the route from parents to children and the other is horizontal transmission among spouses, especially from husband to wife; the anti‐ATLA‐positive family is considered to be a high‐risk group for ATL.