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High‐dose chemotherapy and non‐frozen autologous bone marrow transplantation in relapsed advanced lymphomas or those resistant to conventional chemotherapy
Author(s) -
Carella Angelo M.,
Santini Gino,
Giordano Domenico,
Frassoni Francesco,
Nati Sandro,
Congiu Angela,
Occhini Domenico,
Rossi Edoardo,
Martinengo Marina,
Damasio Eugenio,
Lercari Giuseppe,
Marmont Alberto M.
Publication year - 1984
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19841215)54:12<2836::aid-cncr2820541203>3.0.co;2-r
Subject(s) - medicine , chemotherapy , bone marrow , surgery , bone marrow transplantation , complete remission , lymphoma , transplantation , oncology
Ten patients with advanced, diffuse Hodgkin's and non‐Hodgkin's lymphomas responding poorly to the most widely employed primary chemotherapy regimens were treated with a high‐dose chemotherapy (HDC) followed by rescue with non‐frozen autologous bone marrow infusion (ABMT). Complete remission (CR) was obtained in seven of ten patients (70%) and partial remission in two. Hemopoietic recovery occurred in nine cases. These preliminary results appear to indicate that HDC and non‐frozen ABMT may be successfully used in patients with resistant or relapsed lymphomas.