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Hemangioendothelioma with intravascular coagulation and ischemic colitis
Author(s) -
Weinblatt Mark E.,
Kahn Ellen,
Kochen Joseph A.
Publication year - 1984
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19841115)54:10<2300::aid-cncr2820541041>3.0.co;2-0
Subject(s) - medicine , pathology , coagulopathy , pathophysiology , consumptive coagulopathy , hemangioendothelioma , thigh , ischemic colitis , colitis , disseminated intravascular coagulation , radiology , surgery
An infant who presented with a thigh mass and coagulopathy was found to have a hemangioendothelioma. The tumor rapidly enlarged despite accepted therapeutic modalities, and the child died after a sudden cardiac arrest. Postmortem examination revealed a highly invasive tumor mass that had infiltrated the bowel and involved the inferior mesenteric artery, resulting in ischemic colitis of the left colon. A discussion regarding the pathophysiology with respect to endothelial cell properties and other microscopic features of the tumor is presented.