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Mixed olfactory neuroblastoma and carcinoma. A report of two cases
Author(s) -
Miller Douglas C.,
Goodman Max L.,
Pilch Ben Z.,
Shi Shan Rong,
Dickersin G. Richard,
Halpern Howard,
Norris Charles M.
Publication year - 1984
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19841101)54:9<2019::aid-cncr2820540940>3.0.co;2-p
Subject(s) - ganglioneuroblastoma , neuroblastoma , histogenesis , pathology , adenocarcinoma , medicine , biology , ganglioneuroma , cancer , immunohistochemistry , cell culture , genetics
Two cases of olfactory neuroblastoma mixed with other neoplastic elements are reported. One tumor contained foci of adenocarcinoma and of ganglioneuroblastoma in addition to an undifferentiated small cell component consistent with neuroblastoma; the other tumor histologically resembled small cell undifferentiated carcinoma with foci of squamous differentiation, but was shown by electron microscopy to be neuroblastoma. The histogenesis and treatment of mixed tumors of this type are discussed.