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Pancreatic carcinoma with duct, endocrine, and acinar differentiation. A histologic, immunocytochemical, and ultrastructural study
Author(s) -
Schron Deborah S.,
Mendelsohn Geoffrey
Publication year - 1984
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19841101)54:9<1766::aid-cncr2820540903>3.0.co;2-4
Subject(s) - histogenesis , pathology , endocrine system , enteroendocrine cell , ultrastructure , adenocarcinoma , pancreas , medicine , neuroendocrine differentiation , pancreatic duct , immunohistochemistry , cancer , hormone , prostate cancer
An unusual case of pancreatic carcinoma with components of poorly differentiated adenocarcinoma and islet cell tumor is reported. Histologic, immunocytochemical, and ultrastructural evidence of ductal, endocrine, and exocrine (acinar) differentiation is presented. The implications with regard to endocrine cell differentiation and the histogenesis of pancreatic neoplasms are discussed.