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Papillary adenocarcinomas of the prostate. An immunohistochemical study
Author(s) -
Kuhajda Francis P.,
Gipson Thomas,
Mendelsohn Geoffrey
Publication year - 1984
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19841001)54:7<1328::aid-cncr2820540716>3.0.co;2-f
Subject(s) - histogenesis , immunoperoxidase , prostate , prostatic acid phosphatase , acid phosphatase , immunohistochemistry , medicine , pathology , carcinoma , adenocarcinoma , biology , cancer , enzyme , antibody , biochemistry , immunology , monoclonal antibody
Five cases of papillary adenocarcinomas of the prostate were studied for prostate‐specific acid phosphatase, using the immunoperoxidase method, to determine the origin and histogenesis of these uncommon tumors. All five cases were prostatic‐acid‐phosphatase positive, whereas four cases showed in situ carcinoma involving large periurethral ducts. Positive immunohistochemical localization of prostate‐specific acid phosphatase is useful in identifying papillary carcinoma of true prostatic origin and distinguishing them from prostatic‐acid‐phosphatase‐negative carcinomas which may include tumors arising from periurethral glands or metaplastic urethral mucosa.