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Leukemic meningitis in a patient with hairy cell leukemia. A case report
Author(s) -
Wolfe David W.,
Scopelliti Joseph A.,
Boselli Bruce D.
Publication year - 1984
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19840915)54:6<1085::aid-cncr2820540626>3.0.co;2-s
Subject(s) - medicine , cerebrospinal fluid , hairy cell leukemia , leukemia , meningitis , chemotherapy , bone marrow , central nervous system , pathology , intrathecal , immunology , surgery
Central nervous system involvement has not previously been described in patients with hairy cell leukemia (HCL). A patient is reported who presented with meningeal involvement as his initial symptom of HCL. Diagnosis was established by morphologic and cytochemical studies of his cerebrospinal fluid (CSF) and bone marrow. Treatment with whole‐brain irradiation and intrathecal chemotherapy was successful in clearing leukemic cells from the CSF with resolution of symptoms.