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Melanomas of the mucosa in the oral cavity and the upper respiratory passages
Author(s) -
Berthelsen Anne,
Andersen A. P.,
Jensen T. Skov,
Hansen Hanne Sand
Publication year - 1984
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19840901)54:5<907::aid-cncr2820540526>3.0.co;2-z
Subject(s) - medicine , respiratory mucosa , respiratory system , oral cavity , oral mucosa , mouth mucosa , pathology , dermatology , anatomy , dentistry
Thirty‐eight patients with malignant melanoma of the mucosa in the nasal and oral cavity have been treated at the Radium Centres in Århus, Copenhagen and Odense in the years from 1956 to 1978. Twenty cases were localized to the nasal cavity and the nasal sinuses, and 18 cases to the oral cavity and oropharynx. Twenty‐nine patients had local tumors, eight had local lymph node metastases, and one patient had lung metastases. The primary treatment has been surgery, which was radical in 50% of the cases, whereas 14 patients received irradiation and combined treatment. Complete response was seen locally in five of six irradiated nasal tumors and in three of eight oral tumors. Only two patients with nasal and one patient with oral tumors had recurrence later. Active treatment for recurrence has had the result that 10 patients have survived for 2 additional years, and 1 patient for almost 5 additional years. Eight patients lived for more than 5 years; crude survival is 26%.