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Coexistence of adenocarcinoma and choriocarcinoma in the sigmoid colon
Author(s) -
Kubosawa Hitoshi,
Nagao Koichi,
Kondo Yoichiro,
Ishige Hideo,
Inaba Noriyuki
Publication year - 1984
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19840901)54:5<866::aid-cncr2820540518>3.0.co;2-u
Subject(s) - choriocarcinoma , medicine , adenocarcinoma , malignancy , pathology , sigmoid colon , carcinoma , autopsy , lymph , human chorionic gonadotropin , cancer , rectum , hormone
A rare case of a colon carcinoma that developed in a 50‐year‐old woman is documented. Histologically, the removed tumor was composed of two distinctive elements, i.e., well‐differentiated papillary adenocarcinoma and choriocarcinoma. It was strongly suggested that the latter malignancy derived from the pre‐existing colonic carcinoma through metaplastic proliferation. A very high human chorionic gonadotropin level was noted in the patienťs serum obtained at the preoperative stage. Autopsy materials revealed that metastatic foci in the liver, lungs, and lymph nodes were exclusively composed of choriocarcinoma.