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Enteric‐type adenocarcinoma of the nasal cavity. An electron microscopic and immunocytochemical study
Author(s) -
Batsakis John G.,
Mackay Bruce,
Ordonez Nelson G.
Publication year - 1984
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19840901)54:5<855::aid-cncr2820540516>3.0.co;2-3
Subject(s) - enterochromaffin cell , pathology , immunocytochemistry , enteroendocrine cell , adenocarcinoma , nasal cavity , gastrin , somatostatin , medicine , carcinoma , immunohistochemistry , serotonin , endocrine system , anatomy , cancer , secretion , receptor , hormone
A primary adenocarcinoma of the nasal cavity with light microscopic, electron microscopic, and immunocytochemical features of an enteric‐type carcinoma is presented. The carcinoma contained a variety of dense‐core granules similar to those seen in enterochromaffin cells of different functional types. Some granules demonstrated an immunoreactivity with serotonin, cholecystokinin, gastrin, somatostatin and leu‐enkephalin antibodies. It is suggested that the endocrine cells in the neoplasm belong to the non‐neuroectodermal paraneurone system.