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Osteogenic sarcoma of the fourth thoracic vertebra. Long‐term survival by chemotherapy only
Author(s) -
Ogihara Yoshio,
Sekiguchi Kazuo,
Tsuruta Toyoshi
Publication year - 1984
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19840615)53:12<2615::aid-cncr2820531208>3.0.co;2-s
Subject(s) - medicine , vincristine , doxorubicin , paraplegia , chemotherapy , cyclophosphamide , methotrexate , surgery , sarcoma , vertebra , regimen , chemotherapy regimen , spinal cord , pathology , psychiatry
A unique case of a 15‐year‐old boy with complete paraplegia due to the compression of osteogenic sarcoma at the fourth thoracic vertebra is presented. Because of the difficulty of surgical treatment, he was treated merely by the arterial infusion of Adriamycin (doxorubicin) and systemic chemotherapy in conformity with the cyclophosphamide, Oncovin (vincristine), methotrexate, phenylalanine mustard, Adriamycin (doxorubicin) (COMPADRI)‐III regimen. The patient regained normal function, and has been disease‐free without any neurologic deficit for 6 years. There appears to be some hope for cure using chemotherapy only in otherwise unpromising patients.