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Estrogen receptors and long‐term prognosis in breast cancer
Author(s) -
Aamdal Steinar,
B⊘rmer Ole,
J⊘rgensen Ole,
H⊘st Herman,
Eliassen Gunnar,
Kaalhus Olav,
Pihl Alexander
Publication year - 1984
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19840601)53:11<2525::aid-cncr2820531126>3.0.co;2-8
Subject(s) - medicine , breast cancer , estrogen receptor , oncology , cancer , receptor , estrogen , mammary gland
The long‐term prognosis in 233 primary breast cancer patients, most of whom had received ovarian irradiation, has been related to the estrogen‐receptor status of the primary tumors. The median observation time was 9 years. The receptor status did influence disease‐free interval and survival only in patients having metastases in axillary nodes. Thus, in the postmenopausal patients with axillary metastases, the disease‐free interval and survival time were longer in receptor‐positive than in receptor‐negative patients during the first few years of observation. However, this difference disappeared in the course of the subsequent years. in the premenopausal women with axillary metastases the receptor status did not influence the short‐term prognosis, and, unexpectedly, seemed to affect adversely the long‐term prognosis. It is concluded that the long‐term prognosis is no better in breast cancer patients having estrogen receptors in their primary tumors than in those with receptor‐negative tumors.