Premium
Teratocarcinosarcoma (malignant teratoma?) of the nasal cavity and paranasal sinuses: A clinicopathologic study of 20 cases
Author(s) -
Heffner Dennis K.,
Hyams Vincent J.
Publication year - 1984
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19840515)53:10<2140::aid-cncr2820531025>3.0.co;2-y
Subject(s) - medicine , paranasal sinuses , carcinosarcoma , nasal cavity , neoplasm , teratoma , radiation therapy , surgery , pathology , carcinoma
Twenty cases of a unique type of sinonasal tract neoplasm with combined histologic features of carcinosarcoma and teratoma are described and discussed. The term “teratocarcinosarcoma” is proposed and justified. Patients were adults (age range, 18–79 years; median age, 60 years). The variegated histologic components are illustrated and differences from gonadal germ cell neoplasms are delineated. This neoplastic entity is clearly malignant, with 60% of patients not surviving beyond 3 years (average survival, 1.7 years) following diagnosis, regardless of type of therapy. Aggressive therapy (combined surgery and irradiation) seems justified, however, since 40% of patients survived 3 years or longer with no current evidence of neoplasm (average follow‐up, 6.1 years).