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Skin metastases confined to a field of previous irradiation: Report of two cases and review of the literature
Author(s) -
Diehl Louis F.,
Hurwitz Michael A.,
Johnson Sheldon A.,
Butler William M.,
Taylor H. Grant
Publication year - 1984
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19840501)53:9<1864::aid-cncr2820530912>3.0.co;2-2
Subject(s) - medicine , irradiation , skin tumor , pathology , tumor cells , dermatology , cancer , cancer research , carcinogenesis , physics , nuclear physics
Two cases of tumor recurrence within a previously irradiated skin area are reported. Typical lesions evolve from an erythematous base and progress to induration and tumor papules. A review of clinical literature indicates that irradiation does not increase the frequency of metastases. Experimental data suggest that irradiation does increase metastases as a result of both local mechanical factors and increased tumor‐cell survival.