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Allogeneic bone marrow transplantation in a patient with acute myeloid leukemia secondary to Hodgkin's disease
Author(s) -
de Witte T.,
Blacklock H. A.,
Prentice H. G.,
de Pauw B.,
Haanen C.
Publication year - 1984
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19840401)53:7<1507::aid-cncr2820530714>3.0.co;2-d
Subject(s) - medicine , complete remission , myeloid leukemia , leukemia , disease , bone marrow , surgery , bone marrow transplantation , transplantation , chemotherapy
A patient with Hodgkin's disease entered complete clinical remission by combination radiochemotherapy. He developed dyshematopoiesis 1.5 years later and an overt acute nonlymphocytic leukemia 3 years after diagnosis. A complete remission was achieved following 2 courses of intensive polychemotherapy. Four months later, while still in remission, he underwent an allogeneic bone marrow transplantation (BMT) from an HLA‐identical sister. Mild chronic graft versus host disease of the skin occurred 3 months after BMT, and now the patient has been in complete remission of leukemia for over 2 years. This appears to be a unique case of prolonged remission of a leukemia secondary to an intensively treated Hodgkin's disease.