Premium
Seminoma at roswell park, 1970 to 1979. An analysis of treatment failures
Author(s) -
Huben Robert P.,
Williams Phyllis D.,
Pontes J. Edson,
Panahon Alvin M.,
Murphy Gerald P.
Publication year - 1984
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19840401)53:7<1451::aid-cncr2820530704>3.0.co;2-u
Subject(s) - medicine , seminoma , radiation therapy , chemotherapy , surgery , treatment modality , retrospective cohort study , survival rate
A retrospective study of all cases of seminoma treated at Roswell Park Memorial Institute from 1970 through 1979 was conducted. Fifty‐six evaluable patients treated initially with radiation therapy were seen during this period, and the overall survival rate at an average follow‐up period of 52 months was 82%. The survival rate in patients with bulky abdominal or supradiaphragmatic metastases was only 33% (4 of 12 patients). Treatment failures were analyzed to determine their apparent causes and the implication of such failures to the future management of seminoma. The use of combination chemotherapy as the initial treatment modality in advanced seminoma is discussed in light of these results.