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Vascular invasion in stage I carcinoma of the cervix
Author(s) -
Boyce John G.,
Fruchter Rachel G.,
Nicastri Anthony D.,
Deregt Roberta H.,
Ambiavagar PohChoon,
Reinis Maria,
Macasaet Milagros A.,
Rotman Marvin
Publication year - 1984
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19840301)53:5<1175::aid-cncr2820530524>3.0.co;2-y
Subject(s) - medicine , lesion , cervix , stage (stratigraphy) , vascular invasion , carcinoma , cervical carcinoma , prognostic variable , cervical cancer , pathology , oncology , cancer , biology , paleontology
Vascular invasion was identified as an important prognostic variable for all lesion sizes in 138 patients with Stage I cervical carcinoma. A matched pairs analysis, controlling for lesion size and extracervical spread, showed that vascular invasion was significantly associated with poor outcome. Regression analysis also indicated that vascular invasion contributed prognostic information beyond that available from lesion size and extracervical spread. Studies of adjunctive therapy based on the prognostic variables are recommended. Cancer 53:1175‐1180, 1984.