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Pulmonary metastases in differentiated thyroid carcinoma. Study of 58 cases with implications for the primary tumor treatment
Author(s) -
Massin JeanPierre,
Savoie JeanClaude,
Garnier Henri,
Guiraudon Gérard,
Leger Françoise A.,
Bacourt François
Publication year - 1984
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19840215)53:4<982::aid-cncr2820530427>3.0.co;2-e
Subject(s) - medicine , thyroidectomy , thyroid carcinoma , cervical lymph nodes , papillary carcinoma , carcinoma , thyroid , histology , lymph , follicular carcinoma , primary tumor , gastroenterology , surgery , pathology , metastasis , cancer
Fifty‐eight cases of pulmonary metastases (PM) from 831 cases of differentiated thyroid carcinoma (DTC) were studied. PM were found in about 10% of follicular and 5% of papillary tumors. 131 I uptake was found in 55% of the cases, irrespective of histology. Twenty‐one patients were treated by 131 I only and 12 were cured. Micronodular metastases, 92% papillary, with 86% positive 131 I uptake and 77% 8‐year survival rate, are the most favorable forms. In others the influence of PM size/age, uptake, delay of appearance, presence of cervical or mediastinal lymph nodes is discussed. Occurrence of late PM according to treatment of the primary tumor was 1.3% thyroidectomy + 131 I; 3% thyroidectomy; 5% partial thyroidectomy + 131 I; 11% partial thyroidectomy only. Thus prevention in DTC of severe PM (28% 8‐year survival rate) can best be achieved by complete thyroidectomy + 131 I ablation dose.