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The distribution of blood group substance H and Cea in colorectal carcinoma
Author(s) -
Schoentag Robert,
Williams Valerie,
Kuhns William
Publication year - 1984
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19840201)53:3<503::aid-cncr2820530323>3.0.co;2-j
Subject(s) - carcinoembryonic antigen , medicine , colorectal cancer , distribution (mathematics) , carcinoma , antigen , stage (stratigraphy) , group a , oncology , pathology , gastroenterology , cancer , immunology , mathematical analysis , paleontology , mathematics , biology
The distributional patterns of blood group subtance H and carcinoembryonic antigen (CEA) in 20 colorectal carcinomas from 17 patients, were investigated. Prognosis in these cases was more obviously related to histologic classification and pathologic stage than to BGS and CEA distributional patterns or preoperative plasma CEA levels. The distribution of H and CEA was similar to that found by other investigators for A and B blood group substances with the exception that areas of identical localization could be shown in at least some areas of each tumor studied that was positive for both antigens. The relationship of CEA and BGS is as yet unknown, but it seems probable that they can occur simultaneously in the same tissue.