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Bone marrow necrosis preceding acute lymphoblastic leukemia in childhood
Author(s) -
Niebrugge Daniel J.,
Benjamin Denis R.
Publication year - 1983
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19831201)52:11<2162::aid-cncr2820521131>3.0.co;2-a
Subject(s) - medicine , acute lymphocytic leukemia , bone marrow , leukemia , necrosis , chemotherapy , acute leukemia , lymphoblastic leukemia , childhood cancer , cancer , pathology
Two patients who presented with bone marrow necrosis and eventually developed acute lymphocytic leukemia are reported, and similar cases in the literature are reviewed. Both patients responded to chemotherapy. Several possible mechanisms are discussed. Bone marrow necrosis appears to be another condition preceding acute lymphocytic leukemia in children. Cancer 52:2162‐2164, 1983.