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Ratios of pleural fluid to serum immunoglobulins in malignant pleural effusions
Author(s) -
Desai Suresh D.,
Sackett David L.
Publication year - 1983
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19831201)52:11<2151::aid-cncr2820521129>3.0.co;2-s
Subject(s) - medicine , pleural fluid , pleural effusion , antibody , gastroenterology , pathology , immunology
Pleural fluid and serum protein electrophoresis and quantitative immunoglobulin measurements were carried out in patients with pleural effusions. The mean pleural fluid/serum ratios of IgA, IgG, and IgM were elevated in patients with malignant pleural effusions compared with patients with nonmalignant pleural effusions ( P < 0.04). The sensitivity of a pleural/serum IgA, IgG ratio P > 0.6 was 46%, 69%, respectively, and for IgM ratio > 0.5 was 28%. The specificity for these same ratios was 89%, 74%, and 100% respectively. Cancer 52:2151‐2155, 1983.