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Quantitation of Fc receptor‐bearing T‐lymphocytes (T G and T M ) in oral cancer
Author(s) -
Balaram Prabha,
Vasudevan D. M.
Publication year - 1983
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19831115)52:10<1837::aid-cncr2820521013>3.0.co;2-9
Subject(s) - medicine , receptor , cancer , peripheral blood , immunology , fc receptor , pathology
The lymphocytes from the peripheral blood of 30 untreated patients with oral cancer and 15 apparently healthy normal controls were studied for quantitation of T‐cell subsets. When compared to age‐matched controls, the patients as a group showed a significant increase in the proportion and number of T G cells (IgG Fc receptor‐bearing T‐cells) and a significant reduction in the T M cells (IgM Fc‐bearing T‐cells). The levels of total lymphocytes, T‐cells, and B‐cells remained in the control range. The discrepancy in the T G subset was evident in the early stages of the disease, while in T M cells, it was evident only in the advanced stages.