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A comparison of short‐course, low‐dose and long‐course, high‐dose preoperative radiation for carcinoma of the bladder
Author(s) -
Scanlon Paul W.,
Scott Mark,
Segura Joseph W.
Publication year - 1983
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19831001)52:7<1153::aid-cncr2820520705>3.0.co;2-b
Subject(s) - medicine , cystectomy , bladder cancer , radiation therapy , carcinoma , radiation dose , adjuvant , chemotherapy , urology , survival rate , retrospective cohort study , surgery , oncology , cancer , radiology , nuclear medicine
This retrospective study failed to detect a significant difference in survival rates between patients with bladder carcinoma who underwent cystectomy after short‐course, low‐dose radiation and those who underwent cystectomy after long‐course, high‐dose radiation. The authors were able to identify in the long‐course‐high‐dose group a subset of patients with an unusually good prognosis, but this advantage was not reflected in survival rates. The value of the ability of the long‐course‐high‐dose preoperative technique to identify a subgroup of patients with a relatively good survival rate remains to be determined. In terms of the current management of bladder cancer, this ability to identify a favorable subset of patients is probably not worth the cost and morbidity involved. If, however, adjuvant chemotherapy is to be considered, this ability might be valuable.