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Biclonal lgM gammopathy in a lymphoproliferative disorder
Author(s) -
Gerstein Hal,
Budman Daniel R.,
Schulman Philip,
Vinciguerra Vincent,
Degnan Thomas J.,
Susin Myron
Publication year - 1983
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19830901)52:5<824::aid-cncr2820520513>3.0.co;2-v
Subject(s) - immunoglobulin light chain , medicine , lymphoproliferative disorders , gammopathy , kappa , paraproteinemias , pathology , antibody , immunology , lymphoma , monoclonal , linguistics , philosophy , monoclonal antibody
An unusual case of an IgM producing lymphoproliferative disorder is presented. Using immunoflu‐orescent techniques, this study shows that the heavy chain is associated with kappa light chain in some cells, and with lambda light chain in other cells. This indicates the presence of two distinct malignant cell populations in this patient.