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Chronic granulocytic leukemia following radiation therapy for Hodgkin's disease
Author(s) -
Ritch Paul S.,
Anderson Tom,
Hanson Gerald A.,
Pisciotta Anthony V.
Publication year - 1983
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19830801)52:3<462::aid-cncr2820520314>3.0.co;2-i
Subject(s) - medicine , chronic granulocytic leukemia , busulfan , leukemia , radiation therapy , disease , chronic leukemia , mediastinum , pathology , surgery , acute leukemia , hematopoietic stem cell transplantation
A 33‐year‐old white man was treated with irradiation for Hodgkin's disease involving the mediastinum; four years later he developed typical Philadelphia chromosome‐positive chronic granulocytic leukemia. The patient has been treated with chronic low‐dose busulfan to maintain peripheral blood counts in the normal range and he continues to remain well 27 years after the initial diagnosis of Hodgkin's disease and 23 years following the onset of leukemia.